Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.42 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.42 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.42 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.42 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.42 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.42 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.42 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.42 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037917 | 0.82 | GLA (0.72) | ACACBKMT2AGLAALDH1A1LMNA | |
| SCHEMBL4590122 | 0.81 | KMT2A (0.59) | ACACBKMT2AGLAFAAHPOLB | |
| SCHEMBL97962 | 0.80 | CA2 (0.48) | ACACBKMT2AGLAMEN1POLB | |
| SCHEMBL132095 | 0.79 | POLB (0.51) | ACACBKMT2AGLAMEN1POLB | |
| SCHEMBL9507749 | 0.78 | CASP1 (0.51) | KMT2AGLAFAAHPOLB | |
| SCHEMBL11080137 | 0.75 | LMNA (0.41) | KMT2AGLAMEN1FAAHPOLB | |
| SCHEMBL4589632 | 0.75 | KMT2A (0.54) | KMT2AGLAMEN1FAAHSMN1; SMN2 | |
| SCHEMBL938733 | 0.73 | TGM2 (0.60) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7387003 | 0.73 | CASP1 (0.43) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL6996476 | 0.72 | KMT2A (0.47) | KMT2AGLAMEN1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435397-A | ADRENERGIC BLOCKING AGENTS, 4-(3-ARYLOXY-2-HYDROXYPROPYL) SUBSTITUTED | NIPPON SHINYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |