Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509423 | 0.75 | TSHR (0.35) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL9511730 | 0.72 | ALDH1A1 (0.57) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL10586457 | 0.67 | ALDH1A1 (0.41) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL410250 | 0.65 | PKM (0.76) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL5994567 | 0.65 | PKM (0.76) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL6099389 | 0.65 | PKM (0.76) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL4897654 | 0.65 | ALDH1A1 (0.55) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL20677146 | 0.64 | TDP1 (0.79) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL21094081 | 0.64 | TDP1 (0.79) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL50264 | 0.64 | TDP1 (0.79) | ALDH1A1GLATDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283951-B1 | POLYSACCHARIDE DERIVATIVES CONTAINING ALDEHYDE GROUPS, THEIR PREPARATION FROM THE CORRESPONDING ACETALS AND USE IN PAPER | National Starch and Chemical Investment Holding Corporation (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5011918-A | Siloxane Derivatives Are Useful In Glass Fiber Sizing Compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929670-A | GLASS SIZING COMPOSITIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4839449-A | SIZING COMPOSITION FOR GLASS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0314063-A2 | Polysaccharides containing aromatic aldehydes and their derivatization via amine-aldehyde interactions | National Starch and Chemical Corporation (US) | 1989-05-03 | — | — | EP | disclosed |
| US-4788280-A | Polysaccharide derivatives containing aldehyde groups on an aromatic ring, their preparation from the corresponding acetals and use in paper | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0283951-A1 | Polysaccharide derivatives containing aldehyde groups, their preparation from the corresponding acetals and use in paper | National Starch and Chemical Investment Holding Corporation (US) | 1988-09-28 | — | — | EP | disclosed |