Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046666 | 0.96 | HCAR3 (0.55) | MAPTHCAR3POLBPKMRIPK1 | |
| Water SCHEMBL9652876 | 0.87 | SMN1; SMN2 (0.53) | MAPTHCAR3POLBPKMRIPK1 | |
| SCHEMBL21616838 | 0.85 | SMN1; SMN2 (0.57) | MAPTPOLBSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2061274 | 0.84 | MAPT (0.54) | MAPTHCAR3SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL14294847 | 0.84 | MAPT (0.69) | MAPTHCAR3POLBPKMRIPK1 | |
| SCHEMBL109470 | 0.83 | KMT2A (0.67) | MAPTPKMSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL31365177 | 0.83 | SMN1; SMN2 (0.52) | MAPTHCAR3POLBPKMRIPK1 | |
| SCHEMBL2470932 | 0.82 | KAT2B (0.52) | MAPTPOLBPKMSMN1; SMN2MAPK1 | |
| SCHEMBL9650155 | 0.82 | CHEK1 (0.50) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| Methoxymethane SCHEMBL7082256 | 0.81 | TSHR (0.61) | MAPTPKMSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5009160-A | — | — | None | — | — | JP | disclosed |
| JP-H059160-A | PRODUCTION OF NITROANILINE COMPOUND | L'OREAL SA | 1993-01-19 | — | — | JP | disclosed |
| US-5085666-A | NITROANILINES AND HAIR-DYEING COMPOSITIONS IN WHICH THEY ARE PRESENT | L'OREAL (FR) | 1992-02-04 | — | — | US | disclosed |
| US-4973757-A | Process for the preparation of nitroanilines | L'OREAL (FR) | 1990-11-27 | — | — | US | disclosed |