Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29306545 | 0.95 | HCAR3 (0.67) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL16152114 | 0.94 | HCAR3 (0.66) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL20968369 | 0.94 | HCAR3 (0.66) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL10428098 | 0.94 | HCAR3 (0.66) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL14063303 | 0.91 | HCAR3 (0.65) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL8147273 | 0.91 | MAPT (0.65) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL18469649 | 0.88 | MAPT (0.58) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL18474151 | 0.88 | MAPT (0.61) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL8107611 | 0.87 | MAPT (0.60) | MAPTLMNAMAPK1SMN1; SMN2POLB | |
| SCHEMBL18484959 | 0.86 | MAPT (0.59) | MAPTLMNAMAPK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190125882-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-05-02 | — | — | US | disclosed |
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| US-9867883-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2018-01-16 | — | — | US | disclosed |
| US-9867883-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170044290-A1 | STABLE AND ION-CONDUCTIVE FLUOROPOLYMER-BASED ELECTROLYTES | MIDWEST ENERGY GROUP INC. (US) | 2017-02-16 | — | — | US | disclosed |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2017-02-09 | — | — | US | disclosed |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2017-02-09 | — | — | US | disclosed |
| US-20160206748-A1 | METHOD FOR CONJUGATING MOLECULES | ORGANOLINX CORP. (CA) | 2016-07-21 | — | — | US | disclosed |
| US-20080032917-A1 | FLAVIVIRUS PROTEASE SUBSTRATES AND INHIBITORS | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | AASDHPPT, CA13, CA12 | MAPT 4720/4885LMNA 1646/4885MAPK1 3924/4885 |
| US-20190125882-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | MAPT 4720/4885LMNA 1646/4885MAPK1 3924/4885 |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | MAPT 4720/4885LMNA 1646/4885MAPK1 3924/4885 |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | MAPT 4720/4885LMNA 1646/4885MAPK1 3924/4885 |
| US-20160206748-A1 | METHOD FOR CONJUGATING MOLECULES | AADAC, DDT, ALDH3A1 | MAPT 2425/4885LMNA 3906/4885MAPK1 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.