Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504003 | 0.98 | MTNR1A (0.47) | MTNR1AL3MBTL1HPGDPLA2G10CYP1A1 | |
| SCHEMBL9508056 | 0.97 | MTNR1A (0.46) | MTNR1AL3MBTL1HPGDPLA2G10CYP1A1 | |
| SCHEMBL11739000 | 0.84 | TDP1 (0.57) | L3MBTL1HPGDCYP1A1CYP1B1TDP1 | |
| SCHEMBL11461555 | 0.83 | L3MBTL1 (0.50) | L3MBTL1HPGDCYP1A1CYP1B1TDP1 | |
| Methane SCHEMBL6568809 | 0.83 | TDP1 (0.56) | L3MBTL1HPGDCYP1A1CYP1B1TDP1 | |
| SCHEMBL14064624 | 0.79 | KDM4E (0.46) | HPGDCYP1A1CYP1B1KDM4ELMNA | |
| SCHEMBL5963023 | 0.79 | ALDH1A1 (0.46) | HPGDCYP1A1CYP1B1TDP1KDM4E | |
| SCHEMBL30490817 | 0.79 | KDM4E (0.46) | HPGDCYP1A1CYP1B1KDM4ELMNA | |
| SCHEMBL27480626 | 0.78 | TSHR (0.46) | MTNR1AL3MBTL1HPGDTDP1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28190293 | 0.77 | KDM4E (0.45) | HPGDCYP1A1CYP1B1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |