Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505481 | 0.92 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL9507212 | 0.81 | TDP1 (0.55) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL7492950 | 0.77 | RAB9A (0.62) | TDP1SMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL30072726 | 0.76 | TDP1 (0.60) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL1141627 | 0.76 | TDP1 (0.60) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL29229957 | 0.76 | TDP1 (0.69) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL27843148 | 0.75 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL1616773 | 0.75 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL26132980 | 0.74 | RAB9A (0.57) | TDP1TSHRSMN1; SMN2RECQLNPC1 | |
| SCHEMBL6566097 | 0.74 | S1PR4 (0.38) | TDP1TSHRRECQLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279096-B1 | BENZYL ETHER COMPOUND AND PROCESS FOR PRODUCING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-07-07 | — | — | EP | disclosed |