Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990505 | 0.85 | RAB9A (0.66) | TDP1SMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL9505481 | 0.84 | TDP1 (0.50) | TDP1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL1141627 | 0.82 | TDP1 (0.60) | TDP1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL30072726 | 0.82 | TDP1 (0.60) | TDP1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL9508095 | 0.81 | TDP1 (0.47) | TDP1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL1616773 | 0.81 | TDP1 (0.58) | TDP1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL12194453 | 0.81 | ALDH1A1 (0.46) | TDP1SMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL12218680 | 0.80 | TDP1 (0.54) | TDP1TSHRALDH1A1HTTKMT2A | |
| SCHEMBL2416326 | 0.80 | ALDH1A1 (0.45) | TDP1SMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL13981471 | 0.80 | NPC1 (0.50) | TDP1SMN1; SMN2TSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279096-B1 | BENZYL ETHER COMPOUND AND PROCESS FOR PRODUCING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-07-07 | — | — | EP | claimed |
| US-20170327479-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. | 2017-11-16 | — | — | US | disclosed |
| US-9732052-B2 | Processes and intermediates for making sweet taste enhancers | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160289200-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. | 2016-10-06 | — | — | US | disclosed |
| US-9382196-B2 | Processes and intermediates for making sweet taste enhancers | SENOMYX, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20140107370-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-8586733-B2 | Processes and intermediates for making sweet taste enhancers | SENOMYX, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110245494-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107370-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R50, TAS2R30, TAS2R10 | TDP1 3064/4885SMN1; SMN2 2022/4885TSHR 1708/4885 |
| US-20170327479-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R50, TAS2R30, TAS2R10 | TDP1 3064/4885SMN1; SMN2 2022/4885TSHR 1708/4885 |
| US-20160289200-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R50, TAS2R30, TAS2R10 | TDP1 3064/4885SMN1; SMN2 2022/4885TSHR 1708/4885 |
| US-20110245494-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R50, TAS2R30, TAS2R10 | TDP1 3064/4885SMN1; SMN2 2022/4885TSHR 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.