Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508151 | 1.00 | TNNC1 (0.47) | TNNC1THRATHRBEPHX2FAAH | |
| SCHEMBL9508849 | 0.85 | PPARG (0.45) | FAAHPPARA | |
| SCHEMBL9504795 | 0.85 | PPARG (0.45) | FAAHPPARA | |
| SCHEMBL9508843 | 0.85 | PPARG (0.45) | FAAHPPARA | |
| SCHEMBL11020950 | 0.85 | PPARG (0.45) | FAAHPPARA | |
| SCHEMBL9506054 | 0.84 | TNNC1 (0.45) | TNNC1CNR1CNR2 | |
| SCHEMBL9506051 | 0.84 | TNNC1 (0.45) | TNNC1CNR1CNR2 | |
| SCHEMBL9504667 | 0.84 | EPHX2 (0.47) | EPHX2FAAHPPARA | |
| SCHEMBL9504674 | 0.84 | EPHX2 (0.47) | EPHX2FAAHPPARA | |
| SCHEMBL9506990 | 0.83 | PPARG (0.46) | EPHX2FAAHPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |