Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.37 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | UBE2D3 | P61077 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616713 | 0.72 | ADRA1A (0.50) | POLLADRA1AEPAS1 | |
| SCHEMBL30109346 | 0.69 | MAP3K14 (0.47) | UGT2B17EPAS1MAP3K14 | |
| SCHEMBL9506919 | 0.69 | ALOX5 (0.42) | ALOX5HTR2AUSP2ALDH1A1LMNA | |
| SCHEMBL7096349 | 0.69 | MAP3K14 (0.47) | UGT2B17EPAS1MAP3K14 | |
| SCHEMBL7038617 | 0.67 | HTR2A (0.32) | ALOX5HTR2AUBE2D3 | |
| SCHEMBL24733600 | 0.66 | HTR2A (0.44) | ALOX5HTR2AADRA1AJUN | |
| SCHEMBL31556321 | 0.66 | ALOX5 (0.43) | ALOX5POLLHTR2AADRA1A | |
| SCHEMBL24811429 | 0.64 | CYP3A4 (0.57) | ALOX5ALDH1A1LMNAPOLB | |
| SCHEMBL18688667 | 0.63 | EPAS1 (0.38) | EPAS1MAP3K14 | |
| SCHEMBL24698046 | 0.63 | ERN1 (0.39) | POLLHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |