Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21367505 | 0.79 | ERN1 (0.42) | ALOX5ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL18920026 | 0.77 | PNMT (0.41) | ALOX5HTR2ALMNA | |
| SCHEMBL31556321 | 0.75 | ALOX5 (0.43) | ALOX5HTR2AMEN1KMT2AADRA1A | |
| SCHEMBL8872403 | 0.75 | ERN1 (0.42) | ALOX5ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL25647588 | 0.74 | CASP1 (0.43) | HTR2AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9817570 | 0.72 | ACHE (0.41) | ALDH1A1MAPTNPSR1BRD4MEN1 | |
| SCHEMBL22596240 | 0.72 | EHMT2 (0.36) | ALOX5ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL2722920 | 0.71 | ADRA1A (0.52) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL6314736 | 0.71 | HTR2A (0.36) | ALOX5HTR2AALDH1A1LMNAPOLB | |
| SCHEMBL9510782 | 0.71 | ALDH1A1 (0.53) | ALOX5ALDH1A1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |