Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335759 | 0.83 | HSD11B1 (0.62) | HSD11B1AURKAHIF1ANPSR1SMN1; SMN2 | |
| SCHEMBL18180168 | 0.82 | HSD11B1 (0.54) | HSD11B1AURKAHIF1ANPSR1SMN1; SMN2 | |
| SCHEMBL22341666 | 0.81 | HSD11B1 (0.63) | HSD11B1L3MBTL1AURKAHIF1ANPSR1 | |
| SCHEMBL5803760 | 0.80 | HSD11B1 (0.65) | HSD11B1AURKANAMPT | |
| SCHEMBL6653400 | 0.79 | HSD11B1 (0.58) | HSD11B1L3MBTL1AURKAHIF1ASMN1; SMN2 | |
| SCHEMBL13076421 | 0.77 | HSD11B1 (0.55) | HSD11B1AURKAHIF1ANPSR1SMN1; SMN2 | |
| SCHEMBL11770138 | 0.77 | HSD11B1 (0.58) | HSD11B1AURKAHIF1ASMN1; SMN2KEAP1 | |
| SCHEMBL14008884 | 0.76 | ALDH1A1 (0.50) | HSD11B1AURKAHIF1ANPSR1SMN1; SMN2 | |
| SCHEMBL13544749 | 0.76 | HSD11B1 (0.54) | HSD11B1AURKAHIF1ANPSR1SMN1; SMN2 | |
| SCHEMBL10116308 | 0.75 | HSD11B1 (0.59) | HSD11B1L3MBTL1AURKAHIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297804-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4863846-A | SULFUR | KONICA CORPORATION (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0297804-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1989-01-04 | — | — | EP | disclosed |
| US-4152163-A | Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1979-05-01 | — | — | US | disclosed |