Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020595 | 0.84 | HDAC1 (0.48) | P2RX3GSTP1GSTM2MGLLMEN1 | |
| SCHEMBL11020132 | 0.83 | P2RX3 (0.48) | P2RX3GSTP1GSTM2TGFBR1MEN1 | |
| SCHEMBL9508257 | 0.82 | P2RX3 (0.46) | P2RX3GSTP1GSTM2TGFBR1MEN1 | |
| SCHEMBL9508249 | 0.82 | P2RX3 (0.46) | P2RX3GSTP1GSTM2TGFBR1MEN1 | |
| SCHEMBL25197301 | 0.81 | P2RX3 (0.49) | P2RX3GSTP1GSTM2TGFBR1MGLL | |
| SCHEMBL5020588 | 0.81 | P2RX3 (0.49) | P2RX3GSTP1GSTM2TGFBR1MGLL | |
| SCHEMBL9504669 | 0.80 | MGLL (0.38) | MGLLMEN1KMT2A | |
| SCHEMBL4082004 | 0.80 | GSTP1 (0.49) | P2RX3GSTP1GSTM2TGFBR1MEN1 | |
| SCHEMBL5020590 | 0.79 | P2RX3 (0.45) | P2RX3GSTP1GSTM2MGLLMEN1 | |
| SCHEMBL8228943 | 0.79 | P2RX3 (0.44) | P2RX3GSTP1GSTM2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |