Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508257 | 1.00 | P2RX3 (0.46) | P2RX3TNNC1TGFBR1GSTP1GSTM2 | |
| SCHEMBL9508335 | 0.89 | P2RX3 (0.42) | P2RX3TGFBR1GSTP1GSTM2 | |
| SCHEMBL9508329 | 0.89 | P2RX3 (0.42) | P2RX3TGFBR1GSTP1GSTM2 | |
| SCHEMBL9508263 | 0.82 | P2RX3 (0.48) | P2RX3TGFBR1GSTP1GSTM2MEN1 | |
| SCHEMBL5020591 | 0.78 | P2RX3 (0.50) | P2RX3TGFBR1GSTP1GSTM2MEN1 | |
| SCHEMBL19167335 | 0.77 | GSTP1 (0.48) | P2RX3GSTP1GSTM2MEN1KMT2A | |
| SCHEMBL9508291 | 0.77 | TNNC1 (0.50) | TNNC1 | |
| SCHEMBL9508285 | 0.77 | TNNC1 (0.50) | TNNC1 | |
| SCHEMBL9504734 | 0.76 | EPHX2 (0.37) | TNNC1MEN1KMT2A | |
| SCHEMBL9504744 | 0.76 | EPHX2 (0.37) | TNNC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |