Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590441 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL10711249 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL30159080 | 0.69 | POLB (0.32) | — | |
| SCHEMBL30159039 | 0.69 | POLB (0.32) | — | |
| SCHEMBL10587475 | 0.69 | GRM2 (0.57) | — | |
| SCHEMBL11040462 | 0.69 | GRM2 (0.31) | — | |
| SCHEMBL670563 | 0.67 | — | — | |
| SCHEMBL18695811 | 0.67 | CD81 (0.36) | — | |
| SCHEMBL7557695 | 0.66 | — | — | |
| SCHEMBL9507172 | 0.64 | APLNR (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341475-B1 | STEREO ISOMERS OF N-(R)-1-ARYL-ETHYL)-1-ALKYL-2,2-DICHLOROCYCLOPROPANE CARBOXAMIDE | BAYER AG (DE) | 1993-09-29 | — | — | EP | disclosed |