Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507387 | 0.78 | TDP1 (0.42) | TDP1TSHRHSD17B10 | |
| SCHEMBL712244 | 0.77 | TSHR (0.33) | TDP1TSHR | |
| SCHEMBL9507526 | 0.77 | LMNA (0.41) | TDP1TSHRHSD17B10 | |
| SCHEMBL9507551 | 0.75 | GABRR1 (0.46) | TSHR | |
| SCHEMBL17103149 | 0.74 | TDP1 (0.37) | TDP1TSHR | |
| SCHEMBL9507992 | 0.73 | TDP1 (0.47) | TDP1TSHRHSD17B10 | |
| SCHEMBL9508008 | 0.73 | TDP1 (0.47) | TDP1TSHRHSD17B10 | |
| SCHEMBL8391098 | 0.73 | TDP1 (0.35) | TDP1TSHRHSD17B10 | |
| SCHEMBL9511111 | 0.73 | TDP1 (0.47) | TDP1TSHRHSD17B10 | |
| SCHEMBL11438635 | 0.73 | MAPK1 (0.38) | TDP1MAPK1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |