Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367877 | 0.82 | GABRP (0.31) | TDP1 | |
| SCHEMBL5273525 | 0.82 | TDP1 (0.48) | TSHRTDP1 | |
| SCHEMBL28175661 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL9219277 | 0.78 | THRB (0.46) | TSHRTDP1 | |
| SCHEMBL5793288 | 0.78 | TDP1 (0.32) | TSHRTDP1 | |
| SCHEMBL5793286 | 0.78 | TDP1 (0.32) | TSHRTDP1 | |
| SCHEMBL13678467 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL713454 | 0.78 | — | — | |
| SCHEMBL9508649 | 0.77 | TDP1 (0.39) | TSHRTDP1 | |
| SCHEMBL19680485 | 0.77 | TDP1 (0.35) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237774-B1 | THE USE OF 6-HALOGENO-(1,2,4)-TRIAZOLO-(1,5-a)-PYRIMIDINE COMPOUNDS FOR COMBATING PESTS IN AND ON ANIMALS | MERIAL LTD (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9133209-B2 | Insecticidal 4-amino-thieno[2,3-D]-pyrimidine compounds and methods of their use | MERIAL, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2459569-B1 | INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | MERIAL INC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-9045465-B1 | 3-heterocyclyl-substituted benzoyl derivatives | BASF SE (DE) | 2015-06-02 | — | — | US | disclosed |
| EP-1662877-B1 | 6-HALOGENO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINES FOR COMBATING ANIMAL PESTS | MERIAL LTD (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8664235-B2 | 6-Halogeno-[1,2,4]triazolo[1,5-a]pyrimidines for combating animal pests | MERIAL LIMITED (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120252667-A1 | INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | MERIAL, INC. | 2012-10-04 | — | — | US | disclosed |
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-2459569-A1 | INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | Merial Limited (US) | 2012-06-06 | — | — | EP | disclosed |
| US-8124818-B2 | Method for the production of 3-phenyl(thio) uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-02-28 | — | — | US | disclosed |
| EP-0802905-A1 | SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| WO-1996021645-A1 | SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |
| EP-0169816-B1 | SOLUTIONS OF ANIONIC DYES | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | disclosed |
| US-4648884-A | Solutions of anionic dyes with alkylene glycol mono-alkyl ethers | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4532239-A | N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0054946-B1 | BASIC SUBSTITUTED PYRIDAZINES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054946-A1 | Basic substituted pyridazines, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4216314-A | CARDIOSELECTIVE B-ADRENOLYTIC AGENTS, ANTIARRHYTHMIC AGENTS AND HYPOTENSIVE AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252667-A1 | INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | P2RX2, P2RX5, P2RX1 | TSHR 692/4885TDP1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.