SCHEMBL9508844

SCHEMBL9508844

CCCc1ccc(C#Cc2ccc(OCC)cc2)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 19/20 0.40
NQO1 P15559 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9512376 0.92 ACACB (0.39) ACACBNQO1
SCHEMBL9508900 0.91 MAPT (0.41) ACACBNQO1
SCHEMBL9512429 0.90 ACACB (0.43) ACACB
SCHEMBL9510156 0.90 ACACB (0.39) ACACB
SCHEMBL10511640 0.89 MAPT (0.37) ACACB
SCHEMBL9511434 0.89 APP (0.42) ACACB
SCHEMBL9510145 0.88 NQO1 (0.42) ACACBNQO1
SCHEMBL10302769 0.88 FFAR4 (0.38) ACACB
SCHEMBL9510227 0.88 NR5A1 (0.41) ACACB
SCHEMBL7859812 0.85 FFAR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308438-B1 LIQUID CRYSTAL PHASE CONTAINING TOLANES MERCK PATENT GmbH (DE) 1993-09-29 EP disclosed