Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 7/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511459 | 0.92 | APP (0.41) | APPMCHR1KCNH2MAPTMTNR1A | |
| SCHEMBL9509991 | 0.91 | APP (0.40) | APPMCHR1KCNH2MAPTMTNR1A | |
| SCHEMBL10527260 | 0.89 | MTNR1A (0.36) | APPMCHR1KCNH2MAPTMTNR1A | |
| SCHEMBL9508844 | 0.89 | ACACB (0.40) | ACACB | |
| SCHEMBL9509471 | 0.88 | APP (0.45) | APPMCHR1KCNH2MAPTMTNR1A | |
| SCHEMBL9510156 | 0.87 | ACACB (0.39) | MCHR1ACACB | |
| SCHEMBL9512429 | 0.87 | ACACB (0.43) | MCHR1ACACB | |
| SCHEMBL7859812 | 0.85 | FFAR1 (0.37) | KCNH2MAPT | |
| SCHEMBL9510227 | 0.85 | NR5A1 (0.41) | MCHR1ACACB | |
| SCHEMBL7857686 | 0.85 | ACACB (0.39) | ACACBMAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |