SCHEMBL9508863

SCHEMBL9508863

CC(=O)c1c(Cl)c(Cl)c(C(C)=O)c2c1Sc1cc(Cl)c(Cl)cc1S2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B3 P37058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508968 0.81 MEN1 (0.33) KMT2AMEN1CYP3A4HPGD
SCHEMBL9511203 0.74 AHR (0.34)
SCHEMBL9511243 0.69 SMN1; SMN2 (0.35) KMT2AMEN1CYP3A4HPGD
SCHEMBL29150329 0.66 CES2 (0.42) KMT2AMEN1CYP3A4HPGD
SCHEMBL9510067 0.66 AHR (0.35) KMT2AMEN1CYP3A4HPGD
SCHEMBL7532521 0.65 HPGD (0.52) KMT2AMEN1CYP3A4HPGD
SCHEMBL9510026 0.65 AHR (0.39) KMT2AMEN1CYP3A4HPGD
SCHEMBL12325017 0.64 KMT2A (0.39) KMT2AMEN1CYP3A4HPGD
SCHEMBL27388741 0.64 KMT2A (0.39) KMT2AMEN1CYP3A4HPGD
SCHEMBL9510022 0.64 HSD17B10 (0.43) KMT2AMEN1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed