Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 4/20 | 0.46 |
| ▸ | ALPI | P09923 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477288 | 0.87 | GPR17 (0.50) | ALPLALPIKMT2AALDH1A1TDP1 | |
| SCHEMBL15647681 | 0.81 | MAPT (0.44) | ALPLALPIKMT2AALDH1A1TDP1 | |
| SCHEMBL9763811 | 0.81 | KMT2A (0.44) | ALPLALPIKMT2AALDH1A1TDP1 | |
| SCHEMBL10783122 | 0.81 | FFAR4 (0.53) | ALPLALPIKMT2AALDH1A1TDP1 | |
| SCHEMBL7179842 | 0.81 | VCAM1 (0.62) | ALPLALPITDP1VCAM1 | |
| SCHEMBL11538154 | 0.80 | GPR17 (0.51) | KMT2AALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL31672153 | 0.80 | GPR17 (0.51) | KMT2AALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL9510235 | 0.79 | DHODH (0.47) | ALPLALPIKMT2AALDH1A1TDP1 | |
| SCHEMBL27323918 | 0.78 | ALDH1A1 (0.43) | ALPLALPIKMT2AALDH1A1TDP1 | |
| SCHEMBL217303 | 0.78 | POLB (0.49) | KMT2AALDH1A1TDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288824-B1 | AROMATIC DIAMINES CONTAINING SULFONIC ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYURETHANE POLYMERS | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| US-4797427-A | ESTERIFICATION, HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |