SCHEMBL9508899

SCHEMBL9508899

CC(=NC(C)(C)C)C(=O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508880 1.00 ALDH1A1 (0.30) ALDH1A1TSHRFFAR3LCKFYN
SCHEMBL19565862 0.83 ALDH1A1 (0.33) ALDH1A1TSHRFFAR3LCKFYN
SCHEMBL7093756 0.75 TSHR (0.45) TSHR
SCHEMBL7093754 0.75 TSHR (0.45) TSHR
SCHEMBL2354321 0.73
SCHEMBL241577 0.73
SCHEMBL241578 0.73
SCHEMBL5319817 0.65 LDHA (0.42) ALDH1A1TSHR
Acetone SCHEMBL9320708 0.62 LMNA (0.55) ALDH1A1TSHRFFAR3LCKFYN
SCHEMBL1333138 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281177-B1 A SYNTHESIS FOR BETA-LACTAMS WITH THE AID OF A METAL COMPOUND RIJKSUNIVERSITEIT UTRECHT (NL) 1993-09-01 EP disclosed
EP-0281177-A1 A synthesis for beta-lactams with the aid of a metal compound RIJKSUNIVERSITEIT UTRECHT (NL) 1988-09-07 EP disclosed