Clemizole

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Clemizole SCHEMBL95431	0.92	HIF1A (0.79)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL95609	0.91	HIF1A (0.62)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL95645	0.90	HIF1A (0.64)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL95774	0.90	HIF1A (0.83)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	SCHEMBL95199	0.88	MEN1 (0.64)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL3737473	0.86	HIF1A (0.86)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL29938	0.85	HIF1A (1.00)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	SCHEMBL13559817	0.85	HIF1A (0.76)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL29403196	0.85	HIF1A (1.00)	HIF1ATDP1CYP1A2CYP2D6CYP2C9
	Clemizole SCHEMBL3754755	0.85	HIF1A (0.86)	HIF1ATDP1CYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.