Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clemizole SCHEMBL29938 | 1.00 | HIF1A (1.00) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13187056 | 0.99 | HIF1A (0.97) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL31707402 | 0.99 | HIF1A (1.00) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL19976072 | 0.99 | HIF1A (0.97) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL19976068 | 0.99 | HIF1A (0.97) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL210095 | 0.99 | HIF1A (1.00) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13186938 | 0.99 | HIF1A (0.97) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL19976085 | 0.94 | HIF1A (0.88) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL9444743 | 0.93 | HIF1A (0.86) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 | |
| Clemizole SCHEMBL19976078 | 0.93 | HIF1A (0.86) | HIF1ATDP1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043016-B1 | THE 5HT AGONIST CLEMIZOLE FOR USE IN TREATING EPILEPSY DISORDERS | UNIV CALIFORNIA (US) | 2025-10-29 | — | — | EP | claimed |
| US-20260137654-A1 | COMPOUNDS AND METHODS FOR TREATING AN EPILEPTIC DISORDER | THE REGENTS OF THE UNIV OF CALIFORNIA (US) | 2026-05-21 | — | — | US | disclosed |
| US-20260083706-A1 | 5HT AGONISTS FOR TREATING DISORDERS | UNIV CALIFORNIA (US) | 2026-03-26 | — | — | US | disclosed |
| EP-4696377-A2 | 5HT AGONISTS FOR TREATING DISORDERS | The Regents of the University of California (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4043016-B1 | THE 5HT AGONIST CLEMIZOLE FOR USE IN TREATING EPILEPSY DISORDERS | UNIV CALIFORNIA (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4043016-B1 | THE 5HT AGONIST CLEMIZOLE FOR USE IN TREATING EPILEPSY DISORDERS | UNIV CALIFORNIA (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12447144-B2 | 5HT agonists for treating disorders | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-21 | — | — | US | disclosed |
| US-12419866-B2 | Compounds and methods for treating an epileptic disorder | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-09-23 | — | — | US | disclosed |
| US-12274700-B1 | Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors | Accencio LLC (US) | 2025-04-15 | — | — | US | disclosed |
| CN-119707828-A | Synthesis method of clemizole hydrochloride | 江苏天和制药股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-115667503-A | Compositions and methods for promoting myelination | 儿童医疗中心有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20230003721-A1 | MITOTHERAPEUTICS FOR THE TREATMENT OF BRAIN DISORDERS | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2023-01-05 | — | — | US | disclosed |
| US-20220392567-A1 | MODELLING FRAMEWORK FOR EMBEDDING-BASED PREDICTIONS FOR COMPOUND-VIRAL PROTEIN ACTIVITY | HAMAD BIN KHALIFA UNIVERSITY (QA) | 2022-12-08 | — | — | US | disclosed |
| EP-4045480-A1 | PHARMACEUTICAL FORMULATIONS | First Wave Bio, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |
| EP-4043016-A1 | THE 5HT AGONIST CLEMIZOLE FOR USE IN TREATING EPILEPSY DISORDERS | The Regents of the University of California (US) | 2022-08-17 | — | — | EP | disclosed |
| EP-4043016-A1 | THE 5HT AGONIST CLEMIZOLE FOR USE IN TREATING EPILEPSY DISORDERS | The Regents of the University of California (US) | 2022-08-17 | — | — | EP | disclosed |
| US-20220105057-A1 | METHODS OF TREATMENT | FIRST WAVE BIO, INC. | 2022-04-07 | — | — | US | disclosed |
| EP-3261640-B1 | 5HT AGONISTS FOR TREATING EPILEPSY DISORDERS | UNIV CALIFORNIA (US) | 2022-04-06 | — | — | EP | disclosed |
| US-11291653-B2 | Compounds and methods for treating an epileptic disorder | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-05 | — | — | US | disclosed |
| US-20220079897-A1 | METHODS OF TREATMENT | FIRST WAVE BIO, INC. | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12419866-B2 | Compounds and methods for treating an epileptic disorder | GABRE, SLC6A1, GABBR1 | HIF1A 3168/4885TDP1 2728/4885CYP1A2 226/4885 |
| US-20260083706-A1 | 5HT AGONISTS FOR TREATING DISORDERS | SLC6A4, SLC6A2, TPH2 | HIF1A 4745/4885TDP1 2125/4885CYP1A2 427/4885 |
| US-20220079897-A1 | METHODS OF TREATMENT | ACE2, ACE, SI | HIF1A 4584/4885TDP1 3753/4885CYP1A2 852/4885 |
| US-12274700-B1 | Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors | ACE, SARS1, EIF2AK2 | HIF1A 1313/4885TDP1 2468/4885CYP1A2 4139/4885 |
| US-12447144-B2 | 5HT agonists for treating disorders | HTR1A, HTR5A, HTR2A | HIF1A 4309/4885TDP1 1823/4885CYP1A2 455/4885 |
| US-20220105057-A1 | METHODS OF TREATMENT | ACE2, ACE, SI | HIF1A 4598/4885TDP1 3910/4885CYP1A2 1072/4885 |
| US-20260137654-A1 | COMPOUNDS AND METHODS FOR TREATING AN EPILEPTIC DISORDER | SLC6A13, SLC6A11, SLC6A1 | HIF1A 2676/4885TDP1 2422/4885CYP1A2 636/4885 |
| US-11291653-B2 | Compounds and methods for treating an epileptic disorder | GABRE, SLC6A1, GABBR1 | HIF1A 3168/4885TDP1 2728/4885CYP1A2 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.