SCHEMBL9508937

SCHEMBL9508937

FC(Cl)(Cl)c1nnc(Cl)s1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.37
ALDH1A1 P00352 1/20 0.34
ATM Q13315 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509498 0.85 FBP1 (0.37) FBP1ALDH1A1ATMMEN1KMT2A
SCHEMBL701494 0.82 ALDH1A1 (0.52) FBP1ALDH1A1ATMMEN1KMT2A
SCHEMBL9505469 0.78 FBP1 (0.36) FBP1ALDH1A1ATMMEN1KMT2A
SCHEMBL9505463 0.75 ALDH1A1 (0.35) FBP1ALDH1A1
SCHEMBL10666440 0.69 FBP1 (0.33) FBP1
SCHEMBL6364119 0.67
SCHEMBL31339479 0.60 ALDH1A1 (0.65) ALDH1A1ATMMEN1KMT2AMPI
SCHEMBL10668001 0.59 ALDH1A1 (0.67) FBP1ALDH1A1
SCHEMBL6536981 0.56 FBP1 (0.39) FBP1
SCHEMBL10919280 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348737-B1 HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES BAYER AG (DE) 1993-08-04 EP disclosed
US-5090991-A HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES BAYER AKATIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4968342-A PRE-AND POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0348737-A1 Heteroaryloxy-acetic acid N-isopropyl anilides BAYER AG (DE) 1990-01-03 EP disclosed
US-4791208-A CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1988-12-13 US disclosed
US-4791208-A CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1988-12-13 US disclosed
EP-0148501-B1 5-HALOALKYL-1,3,4-THIADIAZOL-2-YLOXYAMIDES BAYER AG (DE) 1988-05-11 EP disclosed
US-4708731-A PREEMERGENT; CROP PLANT SELECTIVITY BAYER AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
US-4708731-A PREEMERGENT; CROP PLANT SELECTIVITY BAYER AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
EP-0148501-A1 5-Haloalkyl-1,3,4-thiadiazol-2-yloxyamides BAYER AG (DE) 1985-07-17 EP disclosed