Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509498 | 0.82 | FBP1 (0.37) | ALDH1A1ATMMEN1KMT2AMPI | |
| SCHEMBL9505469 | 0.80 | FBP1 (0.36) | ALDH1A1ATMMEN1KMT2AFBP1 | |
| SCHEMBL31339479 | 0.80 | ALDH1A1 (0.65) | ALDH1A1ATMMEN1KMT2AMPI | |
| SCHEMBL9505463 | 0.77 | ALDH1A1 (0.35) | ALDH1A1FBP1 | |
| SCHEMBL10666440 | 0.71 | FBP1 (0.33) | FBP1FFAR2 | |
| SCHEMBL6364119 | 0.69 | — | — | |
| SCHEMBL5077071 | 0.68 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2AMPI | |
| SCHEMBL5077077 | 0.68 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2AMPI | |
| SCHEMBL7829285 | 0.68 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2AMPI | |
| SCHEMBL5074604 | 0.68 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2AMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380771-B | Preparation method of flufenacet | 浙江财和生物科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114380771-A | Preparation method of flufenacet | 浙江财和生物科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| EP-0094541-B1 | SUBSTITUTED 5-TRIFLUOROMETHYL-1,3,4-THIADIAZOL-2-YL OXIACETIC-ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1987-01-14 | — | — | EP | claimed |
| EP-0100038-B1 | PROCESS FOR THE PREPARATION OF THIADIAZOLOXYACETAMIDES | BAYER AG (DE) | 1986-03-05 | — | — | EP | claimed |
| US-4528379-A | Preparation of substituted thiadiazolyloxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-09 | — | — | US | claimed |
| EP-0100038-A1 | Process for the preparation of thiadiazoloxyacetamides | BAYER AG (DE) | 1984-02-08 | — | — | EP | claimed |
| EP-0094541-A2 | Substituted 5-trifluoromethyl-1,3,4-thiadiazol-2-yl oxiacetic-acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1983-11-23 | — | — | EP | claimed |
| WO-2025120168-A1 | SULFONAMIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CRYPTOSPORIDIUM INFECTIONS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) | 2025-06-12 | — | — | WO | disclosed |
| US-12281102-B2 | Inhibitors of APOL1 and methods of using same | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-04-22 | — | — | US | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| CN-118994055-A | Synthesis method of 2-methylsulfonyl-5-trifluoromethyl-1, 3, 4-thiadiazole | 福建永晶科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-114340622-B | Asparagine Endopeptidase (AEP) inhibitors, compositions and uses related thereto | 埃莫里大学 | 2024-11-01 | — | — | CN | disclosed |
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| EP-0100038-B1 | PROCESS FOR THE PREPARATION OF THIADIAZOLOXYACETAMIDES | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0165537-A2 | Process for the preparation of heteroaryloxyacetamides | BAYER AG (DE) | 1985-12-27 | — | — | EP | disclosed |
| US-4528379-A | Preparation of substituted thiadiazolyloxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-09 | — | — | US | disclosed |
| EP-0100038-A1 | Process for the preparation of thiadiazoloxyacetamides | BAYER AG (DE) | 1984-02-08 | — | — | EP | disclosed |
| EP-0094541-A2 | Substituted 5-trifluoromethyl-1,3,4-thiadiazol-2-yl oxiacetic-acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1983-11-23 | — | — | EP | disclosed |
| EP-0094541-A2 | Substituted 5-trifluoromethyl-1,3,4-thiadiazol-2-yl oxiacetic-acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4097669-A | FUNGICIDES, BACTERICIDES, INSECTICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281102-B2 | Inhibitors of APOL1 and methods of using same | APOL1, APOB, NPC1L1 | ALDH1A1 2069/4885ATM 3816/4885MEN1 1767/4885 |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | ALDH1A1 1971/4885ATM 3123/4885MEN1 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.