Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | CPA3 | P15088 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700853 | 0.78 | TDP1 (0.39) | TDP1SMN1; SMN2CPA1CPB1CPA3 | |
| SCHEMBL13464630 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2CPA1CPB1CPA3CPB2 | |
| SCHEMBL30323502 | 0.77 | LMNA (0.49) | SMN1; SMN2CPA1CPB1CPA3CPB2 | |
| SCHEMBL5533761 | 0.74 | CHRM1 (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL5535646 | 0.71 | MAPK1 (0.44) | TDP1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9425696 | 0.70 | KMT2A (0.44) | — | |
| SCHEMBL5533710 | 0.69 | ACE2 (0.49) | — | |
| SCHEMBL5533237 | 0.69 | ACE2 (0.49) | — | |
| SCHEMBL5538410 | 0.69 | ACE2 (0.49) | — | |
| SCHEMBL5531402 | 0.69 | ACE2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552185-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ZENECA LIMITED (GB) | 1993-07-28 | — | — | EP | disclosed |