Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.64 |
| ▸ | RAB9A | P51151 | 14/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | PKM | P14618 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.56 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | METAP2 | P50579 | 3/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174323 | 1.00 | NPC1 (0.64) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30659968 | 0.85 | NPC1 (0.69) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30659969 | 0.85 | NPC1 (0.69) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1535707 | 0.85 | NPC1 (0.69) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2491054 | 0.83 | KDM4E (0.67) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30561047 | 0.80 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30634854 | 0.80 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL172216 | 0.80 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2466325 | 0.79 | RAB9A (0.61) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| Water SCHEMBL9817804 | 0.78 | NPC1 (0.95) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114350230-B | Preparation method of flame-retardant high-hardness epoxy resin floor paint | 深圳市朗迈新材料科技有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-114350230-A | Preparation method of flame-retardant high-hardness epoxy resin floor paint | 深圳市朗迈新材料科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-02-05 | — | — | US | claimed |
| US-6576631-B1 | Broad disease control spectrum; residual effectiveness, rainfastness; nondamaging to crops | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | claimed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | claimed |
| CN-114423173-B | Copper-clad ceramic substrate with high bonding strength and preparation process thereof | 南通威斯派尔半导体技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115697345-A | Preparation of 1,3, 5-triazinylbenzimidazoles | 梅制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697345-A | Preparation of 1,3, 5-triazinylbenzimidazoles | 梅制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697345-A | Preparation of 1,3, 5-triazinylbenzimidazoles | 梅制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114350230-B | Preparation method of flame-retardant high-hardness epoxy resin floor paint | 深圳市朗迈新材料科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| US-20220323449-A1 | (ALPHA-SUBSTITUTED ARALKYLAMINO AND HETEROARYLALKYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES | MEI PHARMA, INC. | 2022-10-13 | — | — | US | disclosed |
| US-20220323449-A1 | (ALPHA-SUBSTITUTED ARALKYLAMINO AND HETEROARYLALKYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES | MEI PHARMA, INC. | 2022-10-13 | — | — | US | disclosed |
| CN-1333768-A | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural bactericides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2002-01-30 | — | — | CN | disclosed |
| CN-1333768-A | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural bactericides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2002-01-30 | — | — | CN | disclosed |
| JP-2001322903-A | GERMICIDAL COMPOSITION FOR AGRICULTURE AND HORTICULTURE | KUMIAI CHEM IND CO LTD | 2001-11-20 | — | — | JP | disclosed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029404-A8 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2000-09-08 | — | — | WO | disclosed |
| WO-2000029404-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | CBR3, TH, CASP3 | NPC1 3727/4885RAB9A 3456/4885KDM4E 840/4885 |
| US-20220323449-A1 | (ALPHA-SUBSTITUTED ARALKYLAMINO AND HETEROARYLALKYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES | CCNI, CCNK, CCNA1 | NPC1 2473/4885RAB9A 1755/4885KDM4E 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.