Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.61 |
| ▸ | NPC1 | O15118 | 13/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | PKM | P14618 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | METAP2 | P50579 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | METAP1 | P53582 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL10887131 | 0.96 | RAB9A (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| Carbazole SCHEMBL11246462 | 0.92 | KDM4E (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7864583 | 0.84 | KDM4E (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL950945 | 0.79 | NPC1 (0.64) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30174323 | 0.79 | NPC1 (0.64) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL172216 | 0.77 | NPC1 (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30561047 | 0.77 | NPC1 (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30634854 | 0.77 | NPC1 (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11153711 | 0.75 | NPC1 (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| Water SCHEMBL9817804 | 0.74 | NPC1 (0.95) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150144198-A1 | SOLAR CELL MATERIALS | CUBICPV INC. | 2015-05-28 | — | — | US | claimed |
| US-20110224147-A1 | METHODS AND COMPOSITIONS | Relevare Aust. Pyt. Ltd. (AU) | 2011-09-15 | — | — | US | claimed |
| US-20100316678-A1 | COMBINATION METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROPATHIC PAIN | CNSBIO PTY LTD. (AU) | 2010-12-16 | — | — | US | claimed |
| EP-2175886-A1 | COMBINATION METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROPATHIC PAIN | CNSBio Pty Ltd (AU) | 2010-04-21 | — | — | EP | claimed |
| WO-2010012043-A1 | METHODS AND COMPOSITIONS | CNSBIO PTY LTD (AU) | 2010-02-04 | — | — | WO | claimed |
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | claimed |
| WO-2009000038-A1 | COMBINATION METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROPATHIC PAIN | CNSBIO PTY LTD (AU) | 2008-12-31 | — | — | WO | claimed |
| EP-1195641-B1 | Film/Screen system and image-forming system for use in direct X-ray applications | AGFA GEVAERT (BE) | 2004-12-29 | — | — | EP | claimed |
| US-6528227-B2 | Radiation-sensitive black-and-white silver halide photographic material in contact with screen sheets designed to emit electrons when exposed to X-rays with an energy greater than or equal to 10 kVp; radiology | AGFA-GEVAERT (BE) | 2003-03-04 | — | — | US | claimed |
| US-6465166-B1 | HIGH SPEED SILVER HALIDE PHOTOGRAPHIC EMULSION WHEREIN THE GRAIN AGGLOMERATION IS PREVENTED AND PHOTOGRAPHIC MATERIAL REDUCED IN RESIDUAL DYE COLOR AFTER PROCESSING | FUJI PHOTO FILM. CO., LTD. (JP) | 2002-10-15 | — | — | US | claimed |
| US-4207103-A | EMULSION CONTAINS ONE ELECTRON ACCEPTING COMPOUND AS DESENSITIZER | EASTMAN KODAK COMPANY (US) | 1980-06-10 | — | — | US | claimed |
| EP-0005652-A2 | Electrophoretic migration imaging process and dispersion | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1979-11-28 | — | — | EP | claimed |
| US-4166740-A | CYANINE DYES | EASTMAN KODAK COMPANY (US) | 1979-09-04 | — | — | US | claimed |
| US-4111699-A | O-NITRO-O-AZAARYLIDENE PHOTOBLEACHABLE DYES AND PHOTOGRAPHIC ELEMENTS UTILIZING THEM | EASTMAN KODAK COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4035190-A | 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-07-12 | — | — | US | claimed |
| US-4028113-A | Photographic supports and elements utilizing photobleachable O-nitroarylidene dyes | EASTMAN KODAK COMPANY (US) | 1977-06-07 | — | — | US | claimed |
| US-3988154-A | Photographic supports and elements utilizing photobleachable omicron-nitroarylidene dyes | EASTMAN KODAK COMPANY (US) | 1976-10-26 | — | — | US | claimed |
| US-3988156-A | Photographic supports and elements utilizing photobleachable o-nitroarylidene dyes | EASTMAN KODAK COMPANY (US) | 1976-10-26 | — | — | US | claimed |
| US-3984248-A | Photographic polymeric film supports containing photobleachable o-nitroarylidene dyes | EASTMAN KODAK COMPANY (US) | 1976-10-05 | — | — | US | claimed |
| US-3935312-A | Combating fungi with imidazo-[4,5-b]quinoxalines | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224147-A1 | METHODS AND COMPOSITIONS | OPRK1, OPRL1, OPRM1 | RAB9A 3055/4885NPC1 1887/4885ALDH1A1 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.