Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196128 | 0.71 | TSHR (0.41) | TSHRCYP1A2CYP2C19PSEN1PSEN2 | |
| SCHEMBL8193018 | 0.70 | TSHR (0.41) | TSHRCYP1A2CYP2C19PSEN1PSEN2 | |
| SCHEMBL6884893 | 0.69 | SLC6A4 (0.57) | NPSR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL26502525 | 0.67 | HDAC4 (0.63) | TSHRHDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL8174124 | 0.66 | TSHR (0.56) | TSHRHDAC8CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31395259 | 0.65 | TSHR (0.43) | TSHRCYP1A2CYP2C9CYP2C19PSEN1 | |
| SCHEMBL12696260 | 0.64 | ACMSD (0.50) | TSHRHDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL36279 | 0.64 | ESR1 (0.52) | TSHRHDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL2379728 | 0.64 | ESR1 (0.52) | TSHRHDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL29350362 | 0.64 | ESR1 (0.52) | TSHRHDAC4HDAC2HDAC8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553346-A1 | PHOTOGRAPHIC PRODUCTS AND PROCESSES | POLAROID CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |