SCHEMBL950958

SCHEMBL950958

CCOC(=O)c1cc(O)nn1-c1ncccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
PDE4B Q07343 1/20 0.43
HSD11B1 P28845 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.41
POLB P06746 2/20 0.40
KDM4E B2RXH2 3/20 0.39
NPC1 O15118 3/20 0.39
MAPT P10636 3/20 0.39
RAB9A P51151 3/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
JMJD6 Q6NYC1 1/20 0.39
BRD4 O60885 1/20 0.38
MEN1 O00255 1/20 0.38
MPI P34949 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMO Q99835 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860005 1.00 ALDH1A1 (0.47) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL29558577 0.89 ALDH1A1 (0.48) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL951462 0.89 SMN1; SMN2 (0.52) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL1762446 0.89 ALDH1A1 (0.48) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL30713046 0.87 ALDH1A1 (0.41) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL30234226 0.87 ALDH1A1 (0.47) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL1762554 0.87 ALDH1A1 (0.47) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL29215224 0.87 ALDH1A1 (0.47) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL13483399 0.87 ALDH1A1 (0.47) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB
SCHEMBL44859 0.87 ALDH1A1 (0.47) ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557931-B Synthesis method of 3-bromo-1- (3-chloro-2-pyridyl) -1H-pyrazole-5-carboxylic acid 浙江新安化工集团股份有限公司 2024-05-14 CN claimed
CN-112552284-A Preparation method of chlorantraniliprole 重庆华歌生物化学有限公司 2021-03-26 CN claimed
CN-111333613-A Preparation method of trifluoromethyl tetralone compound 上海孜岚医药科技有限公司 2020-06-26 CN claimed
EP-4683917-A1 A METHOD FOR THE PREPARATION OF ANTHRANILIC DIAMIDES PI Industries Ltd. (IN) 2026-01-28 EP disclosed
US-12221436-B2 Anthranilamides, their use as insecticide and processes for preparing the same PI INDUSTRIES LTD. (IN) 2025-02-11 US disclosed
WO-2024194896-A1 A METHOD FOR THE PREPARATION OF ANTHRANILIC DIAMIDES PI INDUSTRIES LTD. (IN) 2024-09-26 WO disclosed
US-20240270726-A1 A NOVEL PROCESS FOR THE PREPARATION OF ANTHRANILIC DIAMIDES PI INDUSTRIES LTD. (IN) 2024-08-15 US disclosed
EP-4347586-A1 A NOVEL PROCESS FOR THE PREPARATION OF ANTHRANILIC DIAMIDES PI Industries Ltd. (IN) 2024-04-10 EP disclosed
CN-117412965-A Novel process for the preparation of anthranilic diamides PI工业有限公司 2024-01-16 CN disclosed
WO-2023110710-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023110710-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-7666882-B2 1-(3-Chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-methylethyl)amino]carbonyl]phenyl]-3-(2-propynyloxy)-1H-pyrazole-5-carboxamide; controlling an invertebrate pest; less costly, less toxic, environmentally safer E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-23 US disclosed
US-7666882-B2 1-(3-Chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-methylethyl)amino]carbonyl]phenyl]-3-(2-propynyloxy)-1H-pyrazole-5-carboxamide; controlling an invertebrate pest; less costly, less toxic, environmentally safer E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-23 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12221436-B2 Anthranilamides, their use as insecticide and processes for preparing the same CYP1A2, ANTXR2, DDT ALDH1A1 472/4885PDE4B 1131/4885HSD11B1 1287/4885
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 ALDH1A1 238/4885PDE4B 169/4885HSD11B1 1797/4885
US-20240270726-A1 A NOVEL PROCESS FOR THE PREPARATION OF ANTHRANILIC DIAMIDES RARB, NQO2, RARA ALDH1A1 238/4885PDE4B 555/4885HSD11B1 1328/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT ALDH1A1 436/4885PDE4B 275/4885HSD11B1 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.