SCHEMBL9509711

SCHEMBL9509711

O=[N+]([O-])c1ccc(OC2=NCCO2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 3/20 0.51
HTT P42858 3/20 0.44
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MYOC Q99972 1/20 0.42
ALDH1A1 P00352 2/20 0.41
SRD5A2 P31213 1/20 0.41
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LTA4H P09960 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
POLB P06746 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 0.73 HSPB1 (0.79) HSPB1HTTMEN1KMT2ARAB9A
SCHEMBL11689190 0.73 HSPB1 (0.79) HSPB1HTTMEN1KMT2ARAB9A
SCHEMBL9183872 0.73 HSPB1 (0.79) HSPB1HTTMEN1KMT2ARAB9A
SCHEMBL2011179 0.73 HSPB1 (0.79) HSPB1HTTMEN1KMT2ARAB9A
SCHEMBL5611161 0.72 NOTUM (0.44) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL959666 0.72 HDAC3 (0.46) HTTKMT2ARAB9ANPC1SMN1; SMN2
4,4'-Oxybis(Nitrobenzene) SCHEMBL8934595 0.71 HSPB1 (0.76) HSPB1HTTMEN1KMT2ARAB9A
SCHEMBL29227038 0.69 POLB (0.50) RAB9ANPC1MAPTALDH1A1LMNA
SCHEMBL11552463 0.69 ADRA2A (0.34)
SCHEMBL364168 0.69 HSPB1 (1.00) HSPB1HTTMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP disclosed