Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487981 | 0.82 | LMNA (0.53) | HSP90AB1LMNAPGK1ALDH1A1GAA | |
| SCHEMBL2126605 | 0.77 | HSP90AB1 (0.46) | HSP90AB1LMNAPGK1ALDH1A1GAA | |
| SCHEMBL17466154 | 0.77 | CA12 (0.46) | HSP90AB1LMNAPGK1ALDH1A1GAA | |
| SCHEMBL16068887 | 0.76 | LMNA (0.51) | LMNAALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL7133160 | 0.74 | MAPT (0.49) | HSP90AB1LMNAALDH1A1GAAKDM4E | |
| SCHEMBL837451 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAAKDM4ETP53POLB | |
| SCHEMBL7714633 | 0.73 | ALDH1A1 (0.43) | HSP90AB1LMNAPGK1ALDH1A1GAA | |
| SCHEMBL8261931 | 0.73 | PDGFRB (0.43) | HSP90AB1LMNAPGK1ALDH1A1GAA | |
| SCHEMBL5485173 | 0.73 | PDGFRB (0.43) | HSP90AB1LMNAPGK1ALDH1A1GAA | |
| SCHEMBL31701357 | 0.73 | PDGFRB (0.43) | HSP90AB1LMNAPGK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399293-B1 | PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |
| US-5095157-A | Friedel-crafts catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0399293-A1 | Process for preparing 2-chloro-4-nitro-alkylbenzene | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |