Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | PRCP | P42785 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010135 | 0.82 | HTR2A (0.54) | OPRM1PRCPOPRK1KDM4EGAA | |
| SCHEMBL13507845 | 0.82 | GAA (0.47) | OPRM1PRCPOPRK1KDM4EGAA | |
| SCHEMBL7513639 | 0.82 | TBXA2R (0.49) | PRCPKDM4EGAAMAPTHTT | |
| SCHEMBL5682401 | 0.82 | HTR2A (0.56) | KDM4EGAAMAPTKDM1AADRB2 | |
| Hydrochloric Acid SCHEMBL7510358 | 0.81 | TBXA2R (0.48) | PRCPKDM4EGAAMAPTHTT | |
| SCHEMBL13171804 | 0.79 | ADRB2 (0.46) | KDM4EGAAMAPTHTTKDM1A | |
| SCHEMBL19512604 | 0.77 | MAOA (0.56) | PRCPALDH1A1KDM4EKDM1AHTR2A | |
| SCHEMBL1011743 | 0.77 | MAOA (0.56) | PRCPALDH1A1KDM4EKDM1AHTR2A | |
| SCHEMBL16455043 | 0.77 | PRCP (0.68) | OPRM1PRCPOPRK1ALDH1A1KDM4E | |
| SCHEMBL29768301 | 0.77 | PRCP (0.68) | OPRM1PRCPOPRK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | disclosed |