Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507536 | 1.00 | ACE2 (0.42) | ACE2LTA4HBLMGABRR1CYP1A2 | |
| SCHEMBL9509839 | 0.98 | LTA4H (0.42) | ACE2LTA4HBLMGABRR1CYP1A2 | |
| SCHEMBL9511276 | 0.95 | BLM (0.46) | ACE2LTA4HBLMGABRR1CYP1A2 | |
| SCHEMBL9507515 | 0.90 | GABRR1 (0.42) | ACE2LTA4HBLMGABRR1CYP1A2 | |
| SCHEMBL5537143 | 0.80 | TSHR (0.40) | LTA4HCYP1A2HDAC2TDP1CYP3A4 | |
| SCHEMBL9511261 | 0.79 | MAPT (0.39) | TDP1CYP3A4MAPTCYP2C9TSHR | |
| SCHEMBL9511222 | 0.79 | MAPT (0.39) | TDP1CYP3A4MAPTCYP2C9TSHR | |
| SCHEMBL1524396 | 0.77 | MAPT (0.50) | ACE2LTA4HBLMGABRR1CYP1A2 | |
| SCHEMBL15442569 | 0.77 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL11747978 | 0.77 | MAPT (0.50) | ACE2LTA4HBLMGABRR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |