Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28882910 | 0.84 | TSHR (0.40) | ALDH1A1TSHRGABRR1CYP1A2LMNA | |
| SCHEMBL18270601 | 0.79 | TSHR (0.40) | ALDH1A1TSHRGABRR1CYP1A2LMNA | |
| SCHEMBL6738198 | 0.79 | TSHR (0.40) | ALDH1A1TSHRGABRR1CYP1A2LMNA | |
| SCHEMBL9509857 | 0.79 | ALDH1A1 (0.40) | ALDH1A1GABRR1CYP1A2 | |
| SCHEMBL18270572 | 0.79 | LMNA (0.42) | ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL3912864 | 0.79 | LMNA (0.42) | ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL18270561 | 0.79 | LMNA (0.42) | ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL18270563 | 0.79 | TSHR (0.40) | ALDH1A1TSHRGABRR1CYP1A2LMNA | |
| SCHEMBL6738194 | 0.79 | TSHR (0.40) | TSHRGABRR1CYP1A2LMNAHCAR2 | |
| SCHEMBL6740351 | 0.77 | TSHR (0.39) | TSHRLMNAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |