Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809144 | 0.97 | FOLH1 (0.54) | ALDH1A1CYP1A2CYP2D6CYP2C9FOLH1 | |
| SCHEMBL2919127 | 0.89 | CYP1A2 (0.54) | ALDH1A1CYP1A2CYP2D6CYP2C9FOLH1 | |
| SCHEMBL13165401 | 0.87 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AL3MBTL1MAPK1 | |
| SCHEMBL18782285 | 0.84 | L3MBTL1 (0.63) | ALDH1A1FOLH1NPC1RAB9AL3MBTL1 | |
| SCHEMBL14614752 | 0.84 | L3MBTL1 (0.68) | ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL19022029 | 0.83 | L3MBTL1 (0.71) | ALDH1A1FOLH1NPC1RAB9AL3MBTL1 | |
| SCHEMBL1754823 | 0.82 | NAAA (0.67) | ALDH1A1NPC1RAB9A | |
| SCHEMBL23627359 | 0.81 | L3MBTL1 (0.73) | ALDH1A1FOLH1NPC1RAB9AL3MBTL1 | |
| SCHEMBL24153985 | 0.81 | L3MBTL1 (0.73) | ALDH1A1FOLH1NPC1RAB9AL3MBTL1 | |
| SCHEMBL14679165 | 0.81 | L3MBTL1 (0.73) | ALDH1A1NPC1RAB9AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458886-B1 | AGENTS FOR DIAGNOSING AND TREATING MELANOMAS, AROMATIC HALOGENATED DERIVATIVES USABLE AS SUCH AGENTS AND THEIR PREPARATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-10-13 | — | — | EP | claimed |