SCHEMBL9510070

SCHEMBL9510070

CCCC(c1[c]c(C(C)(C)C)cc(C(C)(C)C)c1)c1[c]c(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4447787 0.76 GABRA1 (0.33)
SCHEMBL11567002 0.74 TP53 (0.38) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL150439 0.72 GABRA1 (0.43) ALOX15CYP2C19
SCHEMBL1720320 0.70 HTR1D (0.36) CYP2C19
SCHEMBL27369343 0.68 GABRA1 (0.33)
SCHEMBL3121979 0.66 GABRA1 (0.39) ALOX15
SCHEMBL1291247 0.66 GABRA1 (0.34) CYP2C19
SCHEMBL248234 0.65 POLB (0.39)
SCHEMBL15067830 0.64 GRIA4 (0.31)
SCHEMBL27341965 0.63 HTR1D (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312790-B1 Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORP (US) 1993-11-18 EP disclosed