SCHEMBL9510076

SCHEMBL9510076

O=S(=O)(F)c1cc2c(cc1Cl)Oc1cc(Cl)c(S(=O)(=O)F)cc1S2

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.37
FLT1 P17948 1/20 0.37
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508123 0.84 AHR (0.38) AHRFLT1CA12CA1CA2
SCHEMBL9511385 0.74 AHR (0.60) AHRFLT1
SCHEMBL9510151 0.71 AHR (0.44) AHRFLT1
SCHEMBL11169418 0.69 L3MBTL1 (0.44) AHRCA12CA1CA2CA3
SCHEMBL9508195 0.69 AHR (0.38) AHRFLT1
SCHEMBL10652247 0.67 AHR (0.44) AHRFLT1
SCHEMBL7764315 0.67 GAA (0.52) CA12CA1CA2CA3CA4
SCHEMBL29447770 0.67 GAA (0.52) CA12CA1CA2CA3CA4
SCHEMBL9508904 0.66 AHR (0.38) AHRFLT1
SCHEMBL9508877 0.65 RAB9A (0.34) AHRFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed