Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.62 |
| ▸ | CTSL | P07711 | 5/20 | 0.62 |
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | CCR1 | P32246 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096307 | 0.88 | CTSB (0.71) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL9096301 | 0.88 | CTSB (0.71) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL6327664 | 0.87 | PREP (0.53) | CTSBCTSLCTSKCTSSPREP | |
| SCHEMBL17704241 | 0.81 | CTSL (0.62) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL6436627 | 0.81 | CTSL (0.62) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL8346816 | 0.81 | CTSL (0.62) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL9510140 | 0.80 | PREP (0.62) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL13502401 | 0.80 | CTSL (0.58) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL9512359 | 0.80 | CTSL (0.58) | CTSBCTSLCTSKCCR1CTSS | |
| SCHEMBL9512349 | 0.80 | CTSL (0.58) | CTSBCTSLCTSKCCR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254545-B1 | DIAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-06 | — | — | EP | disclosed |
| EP-0254545-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |