Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.58 |
| ▸ | CTSK | P43235 | 6/20 | 0.58 |
| ▸ | CTSB | P07858 | 4/20 | 0.58 |
| ▸ | CCR1 | P32246 | 2/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512349 | 1.00 | CTSL (0.58) | CTSLCTSKCTSBCCR1CAPN1 | |
| SCHEMBL9096301 | 0.89 | CTSB (0.71) | CTSLCTSKCTSBCCR1CAPN1 | |
| SCHEMBL9096307 | 0.89 | CTSB (0.71) | CTSLCTSKCTSBCCR1CAPN1 | |
| SCHEMBL13502399 | 0.86 | CTSL (0.58) | CTSLCTSKCTSBCCR1CAPN1 | |
| SCHEMBL13502401 | 0.86 | CTSL (0.58) | CTSLCTSKCTSBCCR1CAPN1 | |
| SCHEMBL9510140 | 0.84 | PREP (0.62) | CTSLCTSKCTSBCCR1DPP4 | |
| SCHEMBL4399079 | 0.82 | CTSL (0.56) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL9656905 | 0.82 | CTSL (0.56) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL5192939 | 0.82 | TRPM8 (0.60) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL15879567 | 0.82 | TRPM8 (0.60) | CTSLCTSKCTSBCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254545-B1 | DIAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-06 | — | — | EP | disclosed |
| EP-0254545-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |