Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697609 | 0.84 | — | — | |
| SCHEMBL4432419 | 0.78 | — | — | |
| SCHEMBL285102 | 0.78 | — | — | |
| SCHEMBL1695186 | 0.69 | — | — | |
| SCHEMBL15074706 | 0.69 | RAB9A (0.36) | HPGDHTTALDH1A1RAB9AKDM4E | |
| SCHEMBL1695183 | 0.67 | NPC1 (0.39) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL22127290 | 0.67 | HPGD (0.30) | HPGDHTT | |
| SCHEMBL15799592 | 0.65 | ITGB3 (0.41) | HPGDHTTALDH1A1RAB9AKDM4E | |
| SCHEMBL19112078 | 0.65 | POLB (0.38) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL22604966 | 0.65 | USP2 (0.43) | HPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274721-B1 | POLYMERS CONTAINING AMINO GROUPS, THEIR MANUFACTURE AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0272664-B1 | CURABLE MIXTURES AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| EP-0272664-A2 | Curable mixtures and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-29 | — | — | EP | disclosed |