SCHEMBL15074706

SCHEMBL15074706

CNC(=O)C1COC(=O)O1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.36
NPC1 O15118 6/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
HPGD P15428 3/20 0.36
POLB P06746 2/20 0.35
HTT P42858 2/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 2/20 0.34
NPSR1 Q6W5P4 3/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16491486 0.80 RAB9A (0.38) RAB9ANPC1L3MBTL1HPGDPOLB
SCHEMBL19112078 0.79 POLB (0.38) RAB9ANPC1L3MBTL1HPGDPOLB
SCHEMBL22604966 0.79 USP2 (0.43) RAB9ANPC1L3MBTL1HPGDPOLB
SCHEMBL12035164 0.78
SCHEMBL1695183 0.78 NPC1 (0.39) RAB9ANPC1L3MBTL1HPGDHTT
SCHEMBL19320495 0.77 HPGD (0.31) HPGDPOLB
SCHEMBL1695186 0.76
SCHEMBL19320497 0.75 POLB (0.42) RAB9ANPC1HPGDPOLBHTT
SCHEMBL13923633 0.74 RAB9A (0.65) RAB9ANPC1L3MBTL1HPGDPOLB
SCHEMBL15057288 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200165373-A1 CURABLE ORGANIC POLYMER COMPRISING AT LEAST ONE ACYLUREA UNIT, ITS PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2020-05-28 US disclosed
US-10590227-B2 Curable organic polymer comprising at least one acylurea unit, its preparation and use CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2020-03-17 US disclosed
WO-2017207461-A1 USE OF COMPOUNDS HAVING N 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE UNITS IN TWO-COMPONENT ADHESIVES BASF SE (DE) 2017-12-07 WO disclosed
US-20170253687-A1 A CURABLE ORGANIC POLYMER COMPRISING AT LEAST ONE ACYLUREA UNIT, ITS PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2017-09-07 US disclosed
US-20170253687-A1 A CURABLE ORGANIC POLYMER COMPRISING AT LEAST ONE ACYLUREA UNIT, ITS PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2017-09-07 US disclosed
US-9617238-B2 2-oxo-1,3-dioxolane-4-carboxamide building blocks, their preparation and use CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2017-04-11 US disclosed
US-9617238-B2 2-oxo-1,3-dioxolane-4-carboxamide building blocks, their preparation and use CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2017-04-11 US disclosed
US-20170008871-A1 2-HYDROXYETHYL 2-OXO-1,3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2017-01-12 US disclosed
US-20170008871-A1 2-HYDROXYETHYL 2-OXO-1,3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2017-01-12 US disclosed
EP-2794585-B1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE CONSTR RES & TECH GMBH (DE) 2016-06-15 EP disclosed
EP-2998331-A1 A curable organic polymer comprising at least one acylurea unit, its preparation and use Construction Research & Technology GmbH (DE) 2016-03-23 EP disclosed
US-20150353521-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2015-12-10 US disclosed
US-20150353521-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2015-12-10 US disclosed
WO-2015132080-A1 2-HYDROXYETHYL 2-OXO-1, 3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2015-09-11 WO disclosed
EP-2915808-A1 2-Hydroxyethyl 2-oxo-1,3-dioxolane-4-carboxylates, their preparation and use Construction Research & Technology GmbH (DE) 2015-09-09 EP disclosed
US-20150051365-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2015-02-19 US disclosed
US-20150051365-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2015-02-19 US disclosed
WO-2014118268-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2014-08-07 WO disclosed
EP-2762471-A1 2-oxo-1,3-dioxolane-4-carboxamide building blocks, their preparation and use Construction Research & Technology GmbH (DE) 2014-08-06 EP disclosed
WO-2013092011-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353521-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE PYCR1, CBR1, NOX4 RAB9A 3478/4885NPC1 1994/4885L3MBTL1 4649/4885
US-20170008871-A1 2-HYDROXYETHYL 2-OXO-1,3-DIOXOLANE-4-CARBOXYLATES, THEIR PREPARATION AND USE HAO2, OXGR1, HAO1 RAB9A 4062/4885NPC1 4820/4885L3MBTL1 2812/4885
US-20150051365-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE HAO2, OXGR1, AOX1 RAB9A 4494/4885NPC1 4149/4885L3MBTL1 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.