SCHEMBL95104

SCHEMBL95104

[CH2]Oc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 7/20 0.50
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
KCNA3 P22001 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 3/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
PGR P06401 1/20 0.46
GAA P10253 1/20 0.46
PTGS1 P23219 1/20 0.46
MAPK1 P28482 1/20 0.46
HTR1D P28221 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC6A4 P31645 2/20 0.44
CYP1A2 P05177 2/20 0.44
HRH1 P35367 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778935 0.87 HPRT1 (0.58) HTR1BALDH1A1TDP1HPGDHSD17B10
SCHEMBL2783372 0.82 HSD17B10 (0.48) HTR1BALDH1A1KDM4ETDP1KCNA3
Ethylene SCHEMBL4726812 0.80 HTR1B (0.50) HTR1BALDH1A1KDM4ETDP1KCNA3
SCHEMBL2783440 0.79 NQO1 (0.43) HTR1BALDH1A1KDM4EKCNA3HPGD
SCHEMBL442767 0.79 HTR1B (0.54) HTR1BALDH1A1KDM4ETDP1KCNA3
SCHEMBL29577853 0.79 HTR1B (0.54) HTR1BALDH1A1KDM4ETDP1KCNA3
SCHEMBL4289478 0.79 HTR1B (0.59) HTR1BALDH1A1KDM4ETDP1KCNA3
Lithium SCHEMBL6571336 0.77 HTR1B (0.52) HTR1BALDH1A1KDM4ETDP1KCNA3
SCHEMBL7457103 0.77 HTR1B (0.52) HTR1BALDH1A1KDM4ETDP1KCNA3
Methane SCHEMBL10959030 0.77 HTR1B (0.52) HTR1BALDH1A1KDM4ETDP1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024037851-A1 USE OF ADDITIVES FOR IMPROVING THE PROCESSING OF POLYETHYLENES BASF SE (DE) 2024-02-22 WO claimed
EP-3475085-B1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-05 EP claimed
CN-109694350-B Compound containing fluoromethyl and preparation method thereof 中国科学院上海有机化学研究所 2023-05-09 CN claimed
CN-110885292-B Synthesis method of beta-aminoalcohol compound 云南大学 2022-10-28 CN claimed
CN-109195795-B Multilayer film and package formed therefrom 陶氏环球技术有限责任公司 2022-02-18 CN claimed
EP-3237521-B1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-27 EP claimed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP claimed
CN-107108963-B Polyethylene composition with improved optical properties 陶氏环球技术有限责任公司 2020-04-21 CN claimed
CN-110885292-A β -amino alcohol compound synthesis method 云南大学 2020-03-17 CN claimed
US-10316168-B2 Polyethylene compositions with improved optical properties DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-11 US claimed
US-4591591-A FOR TREATING HEART FAILURE ELI LILLY AND COMPANY (US) 1986-05-27 US claimed
EP-0080718-B1 INTER-M-PHENYLENE-PGI2 DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1986-05-14 EP claimed
EP-0161918-A2 Indoline and 2-indolinone derivatives ELI LILLY AND COMPANY (US) 1985-11-21 EP claimed
EP-0155798-A1 Pyridazone inotropic agents ELI LILLY AND COMPANY (US) 1985-09-25 EP claimed
EP-0151006-A2 Dihydropyridine compounds, their production, pharmaceutical compositions containing them, and methods of producing these compositions YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1985-08-07 EP claimed
EP-0132508-A2 Hydroxyethyl-azolyl derivatives, their use and antiviral agents containing them BAYER AG (DE) 1985-02-13 EP claimed
EP-0111711-A2 Heterocyclically substituted hydroxyalkyl-azolyl derivatives BAYER AG (DE) 1984-06-27 EP claimed
EP-0111146-A2 Anti-mycotic hydroxyalkyl-azolyl derivatives BAYER AG (DE) 1984-06-20 EP claimed
US-4112219-A Acyl derivatives of antibiotic BM123γ AMERICAN CYANAMID COMPANY (US) 1978-09-05 US claimed
US-4100285-A VASODILATION NIPPON SHINYAKU CO., LTD. (JP) 1978-07-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10316168-B2 Polyethylene compositions with improved optical properties PARG, PARN, FHIT HTR1B 3341/4885ALDH1A1 4816/4885KDM4E 1145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.