Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitroquinoline-1-Oxide SCHEMBL29367999 | 0.82 | MAPT (0.56) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL21114410 | 0.82 | MAPT (0.56) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL105454 | 0.82 | MAPT (0.56) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL140249 | 0.78 | MAPT (0.51) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| SCHEMBL2796338 | 0.72 | TDP1 (0.59) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| Nitrobenzene SCHEMBL28079888 | 0.70 | ALDH1A1 (0.55) | MAPTRAB9AS1PR4HTTTDP1 | |
| SCHEMBL7464842 | 0.68 | MAPT (0.48) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| SCHEMBL16704752 | 0.66 | MAPT (0.53) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| SCHEMBL3341802 | 0.65 | TSHR (0.49) | MAPTRAB9AKDM4ENPC1S1PR4 | |
| SCHEMBL3342386 | 0.65 | TSHR (0.49) | MAPTRAB9AKDM4ENPC1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324258-B1 | PROCESS FOR DETECTING POTENTIAL CARCINOGENS | GeneBioMed, Inc. (US) | 1993-08-18 | — | — | EP | disclosed |