Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172818 | 0.90 | ABCB1 (0.47) | ABCB1 | |
| SCHEMBL9815851 | 0.87 | ABCB1 (0.43) | ABCB1POLB | |
| SCHEMBL9815860 | 0.85 | ABCB1 (0.45) | ABCB1POLB | |
| SCHEMBL10719304 | 0.84 | ABCB1 (0.56) | ABCB1POLB | |
| SCHEMBL9815886 | 0.83 | CTNNB1 (0.52) | ABCB1POLB | |
| SCHEMBL8173237 | 0.82 | POLB (0.68) | POLB | |
| SCHEMBL9815835 | 0.81 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL9510944 | 0.81 | KDM4E (0.49) | ABCB1KDM4EALDH1A1 | |
| SCHEMBL9714356 | 0.80 | POLB (0.70) | ABCB1POLB | |
| SCHEMBL9815854 | 0.79 | ABCB1 (0.58) | ABCB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |