Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815800 | 0.91 | POLB (0.56) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL9511093 | 0.90 | AGTR1 (0.55) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL8166298 | 0.89 | POLB (0.68) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL9425189 | 0.87 | HPGD (0.68) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9815864 | 0.87 | ABCB1 (0.60) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9426130 | 0.86 | POLB (0.72) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9425567 | 0.85 | POLB (0.63) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9425890 | 0.84 | TLR7 (0.64) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL9509589 | 0.84 | MEN1 (0.57) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL9815862 | 0.84 | POLB (0.65) | POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013836-A | PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY | ROHM AND HAAS COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-5424333-A | Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines | ROHM AND HAAS COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |