Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065330 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29901519 | 0.66 | TRPA1 (0.31) | — | |
| SCHEMBL19983 | 0.66 | TRPA1 (0.31) | — | |
| SCHEMBL3063701 | 0.66 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29014765 | 0.66 | CA12 (0.45) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL31238829 | 0.66 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL433359 | 0.64 | TRPA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7403491 | 0.64 | TRPA1 (0.31) | — | |
| SCHEMBL3084502 | 0.64 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL3073175 | 0.64 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302379-B1 | NAPHTHOTHIAZEPINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-29 | — | — | EP | claimed |
| CN-1031082-A | Aphthothiazoles product derivative and its preparation method | TANABE SEIYAKU CO (JP) | 1989-02-15 | — | — | CN | claimed |
| EP-0302379-A1 | Naphthothiazepine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-02-08 | — | — | EP | claimed |
| EP-0302379-B1 | NAPHTHOTHIAZEPINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| CN-1017151-B | PROCESSES FOR PREPARING NAPHTHOTHIAZEPINE DERIVATIVE | TANABE SEIYAKU CO (JP) | 1992-06-24 | — | — | CN | disclosed |
| EP-0302379-A1 | Naphthothiazepine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302379-A1 | Naphthothiazepine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |