Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034864 | 0.92 | — | — | |
| Succinic Acid SCHEMBL29506593 | 0.82 | ITGB3 (0.35) | NPC1MAP3K14CRBNDDB1GAA | |
| SCHEMBL5318696 | 0.78 | NPC1 (0.44) | NPC1MAP3K14CRBNDDB1GAA | |
| SCHEMBL9510783 | 0.78 | MAP3K14 (0.40) | NPC1MAP3K14CRBNDDB1GAA | |
| Propane SCHEMBL11082339 | 0.76 | MAP3K14 (0.39) | NPC1MAP3K14CRBNDDB1GAA | |
| SCHEMBL28153842 | 0.74 | NPC1 (0.48) | NPC1MAP3K14CRBNDDB1LMNA | |
| SCHEMBL10754755 | 0.73 | MAP3K14 (0.48) | NPC1MAP3K14CRBNDDB1GAA | |
| SCHEMBL8348991 | 0.73 | MAP3K14 (0.48) | NPC1MAP3K14CRBNDDB1GAA | |
| SCHEMBL114367 | 0.73 | NPC1 (0.36) | NPC1MAP3K14CRBNDDB1GAA | |
| Butane SCHEMBL11081473 | 0.73 | GLA (0.41) | NPC1MAP3K14CRBNDDB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460782-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |