Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065483 | 0.88 | NPC1 (0.37) | NPC1MAP3K14CRBNDDB1GLA | |
| SCHEMBL2573071 | 0.84 | NPC1 (0.40) | NPC1CRBNDDB1LMNAMAPT | |
| SCHEMBL112502 | 0.82 | NPC1 (0.40) | NPC1CRBNDDB1LMNAMAPT | |
| SCHEMBL6272873 | 0.82 | NPC1 (0.40) | NPC1CRBNDDB1LMNAMAPT | |
| SCHEMBL1028530 | 0.81 | MAP3K14 (0.39) | NPC1MAP3K14CRBNDDB1GLA | |
| SCHEMBL17065492 | 0.81 | MAP3K14 (0.33) | MAP3K14GLA | |
| SCHEMBL8909758 | 0.80 | MAP3K14 (0.32) | MAP3K14 | |
| SCHEMBL193688 | 0.77 | MAP3K14 (0.39) | MAP3K14CRBNDDB1LMNAMAPT | |
| SCHEMBL114517 | 0.76 | GLA (0.37) | MAP3K14CRBNDDB1GLAGAA | |
| SCHEMBL29868031 | 0.76 | CRBN (0.47) | CRBNDDB1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424947-A1 | COMPOSITIONS AND METHODS INCORPORATING PHOTOCATALYSTS | The Procter & Gamble Company (US) | 2012-03-07 | — | — | EP | disclosed |
| EP-2384457-A2 | COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2011-11-09 | — | — | EP | disclosed |
| EP-2273968-A1 | COMPOSITIONS AND METHODS INCORPORATING PHOTOCATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2010126919-A1 | COMPOSITIONS AND METHODS INCORPORATING PHOTOCATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010055406-A2 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2009140076-A1 | COMPOSITIONS AND METHODS INCORPORATING PHOTOCATALYSTS | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |