Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510982 | 1.00 | APP (0.50) | APPPPARGMEN1KMT2AMAPT | |
| SCHEMBL7476612 | 0.90 | ATM (0.50) | PPARGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9655690 | 0.83 | PPARG (0.46) | PPARGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7845708 | 0.83 | ATM (0.53) | MEN1KMT2AMAPTALDH1A1ATM | |
| SCHEMBL15628261 | 0.82 | MMP14 (0.53) | PPARGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9512188 | 0.82 | ALDH1A1 (0.41) | APPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9512183 | 0.82 | ALDH1A1 (0.41) | APPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9512215 | 0.80 | APP (0.60) | APPPPARGMEN1KMT2AMAPT | |
| SCHEMBL9512221 | 0.80 | APP (0.60) | APPPPARGMEN1KMT2AMAPT | |
| SCHEMBL30969410 | 0.79 | MAPT (0.43) | PPARGMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350112-B1 | POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| US-5001209-A | Non-linear optical active diols and polyurethanes prepared therefrom | AKZO N.V. (NL) | 1991-03-19 | — | — | US | disclosed |
| EP-0350112-A1 | Polyurethanes prepared from non-linear optical active diols | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |